Intravesical injection of botulinum toxin is a treatment for the Overactive bladder syndrome, with or without associated urinary incontinence.
Alternative therapies, when oral treatment is ineffective or has undesirable side effects, may also include sacral root nerves neuromodulation and PTNS. The choice of the best candidates for each therapeutic modality depends on the clinical case and specific situation of each patien, such as associated diseases and often findings from the Urodynamic study, usually performed prior to a second line treatment.
Using a urethrocystoscope for direct visualization, the drug is injected directly into the bladder wall using a specifically designed needle. The procedure is performed under local anesthesia, which is introduced into the bladder 15 minutes earlier through a low caliber tube.
After the injection, the patient can return home without the need for hospitalization or recovery, given the minimally invasive nature of the procedure and the use of local anesthesia.